Vancomycin-intermediate Staphylococcus aureus with phenotypic susceptibility to methicillin in a patient with recurrent bacteremia.

نویسندگان

  • Timothy S Naimi
  • Daniel Anderson
  • Carol O'Boyle
  • David J Boxrud
  • Susan K Johnson
  • Fred C Tenover
  • Ruth Lynfield
چکیده

Vancomycin-intermediate Staphylococcus aureus (VISA) are an emerging problem. We observed a statistically significant inverse relationship in the MICs of vancomycin and oxacillin in S. aureus isolates from a patient undergoing hemodialysis who received 26 weeks of treatment with vancomycin during November 1999 through April 2000. All isolates were mecA positive and were indistinguishable by pulsed-field gel electrophoresis. The evolving susceptibility patterns of this strain highlight the challenges of detecting and treating VISA infections.

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1. Woods CW, Cheng AC, Fowler VG Jr, et al. Endocarditis caused by Staphylococcus aureus with reduced susceptibility to vancomycin. Clin Infect Dis 2004; 38:1188–91. 2. Centers for Disease Control and Prevention (CDC). Investigation and control of vancomycin-intermediate and -resistant Staphylococcus aureus: a guide for health departments and infection control personnel. Atlanta, GA: CDC, 2004....

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عنوان ژورنال:
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

دوره 36 12  شماره 

صفحات  -

تاریخ انتشار 2003